PubMed COVID-19 Clinical Care
8441 - 8450 of 44979 results found
Vaccination against COVID-19 - risks and benefits in children
Description
Countries in Europe and around the world have taken varying approaches to their policies on COVID-19 vaccination for children. The low risk of severe illness from COVID-19 means that even small risks from vaccination warrant careful consideration
Adaptation of SARS-CoV-2 to ACE2H353K mice reveals new spike residues that drive mouse infection
Description
We developed a new mouse model with a humanized angiotensin converting enzyme 2 (ACE2) locus that preserves native regulatory elements. A single point mutation in mouse ACE2 (H353K) was sufficient to confer in vivo infection with ancestral severe
A distinctive evolution of alveolar T cell responses is associated with clinical outcomes in unvaccinated patients with SARS-CoV-2 pneumonia
Description
Pathogen clearance and resolution of inflammation in patients with pneumonia require an effective local T cell response. Nevertheless, local T cell activation may drive lung injury, particularly during prolonged episodes of respiratory failure
A broadly generalizable stabilization strategy for sarbecovirus fusion machinery vaccines
Description
Continuous evolution of SARS-CoV-2 alters the antigenicity of the immunodominant spike (S) receptor-binding domain and N-terminal domain, undermining the efficacy of vaccines and monoclonal antibody therapies. To overcome this challenge, we set out
Insights into medical students' perceptions of work culture during the COVID-19 pandemic: a mixed method study
Description
CONCLUSIONS: The analysis highlighted the importance of students being able to adapt and draw on a range of resources during the COVID-19 pandemic. This underscores the need for work cultures that support adaptability and coping. Further research is
Archetypal analysis of COVID-19 in Montana, USA, March 13, 2020 to April 26, 2022
Description
Infectious disease data can often involve complex spatial patterns intermixed with temporal trends. Archetypal Analysis is a method to mine complex spatio-temporal data, and can be used to discover the dynamics of spatial patterns. The application of
Predicting Public Cooperation with Face Covering at the Early Phases of COVID-19: Building Public Trust, Confidence, Knowledge Through Governmental Two-Way Symmetrical Communication
Description
Despite the agreement on the importance of two-way communication during governmental response to pandemics, few studies provided empirical evidence to support the effectiveness of such communication strategy in times of a public health crisis
Effects of online education on prosthetics orthotics education during COVID-19
Description
CONCLUSION: Both academicians and students experienced connection problems, and applied courses were not suitable for online education. Motivation to attend the courses was low in online education, relevant workload increased, online examinations
Inpatient Costs of Treating Patients With COVID-19
Description
CONCLUSIONS AND RELEVANCE: In this cross-sectional study, an adjusted mean hospital cost to provide care for patients with COVID-19 increased more than 5 times the rate of medical inflation overall. This appeared to be explained partly by changes in
