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Research
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PubMed COVID-19 Clinical Care

6331 - 6340 of 44979 results found

A speed limit on serial strain replacement from original antigenic sin

Date
Tuesday, January 23, 2024 - 4:00 AM
Description
Many pathogens evolve to escape immunity, yet it remains difficult to predict whether immune pressure will lead to diversification, serial replacement of one variant by another, or more complex patterns. Pathogen strain dynamics are mediated by cross

Daily positive and negative affect during the COVID-19 pandemic

Date
Tuesday, January 23, 2024 - 4:00 AM
Description
The COVID-19 pandemic influenced emotional experiences globally. We examined daily positive and negative affect between May/June 2020 and February 2021 (N = 151,049; 3,509,982 observations) using a convenience sample from a national mobile

Doing research in non-specialist mental health services for children and young people: lessons learnt from a process evaluation of the ICALM (Interpersonal Counselling for Adolescent Low Mood) feasibility randomised controlled trial

Date
Tuesday, January 23, 2024 - 4:00 AM
Description
CONCLUSIONS: Conducting a RCT of IPC-A in non-specialist services is not feasible in the current context. Failure to conduct effectiveness trials in this setting has clinical implications, potentially resulting in escalation of mild mental health